Increased Ca 2+ buffering enhances Ca 2+ ‐dependent process
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چکیده
منابع مشابه
Increased Ca buffering enhances Ca-dependent process
The title for this Perspectives article must have a misprint – surely, it should say, ‘Increased Ca buffering diminishes Ca-dependent process’. In fact, the title is correct, as shown in the startling results reported in a remarkable study appearing in this issue of The Journal of Physiology (Rozov et al. 2001). The venerable Neher and Sakmann team has rejoined forces, combining the talents of ...
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18 Thalamic paraventricular nucleus (PVT) neurons exhibit a post-burst apamin-resistant 19 slow afterhyperpolarization (sAHP) that is unique to midline thalamus, displays activity 20 dependence and is abolished in tetrodotoxin. Analysis of the underlying sIAHP confirmed a 21 requirement for Ca influx with contributions from P/Q-, N-, Land R subtype channels, a 22 reversal potential near EK and ...
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A calcium-dependent regulator protein has previously been characterized (Dedman, J. R., Potter, J. D., Jackson, R. L., Johnson, J. D., and Means, A. R. (1977) J. Biol. Chem. 252, 8415-8422) and the primary sequence determined (Dedman, J. R., Jackson, R. L., Schreiber, W. E., and Means, A. R. (1978) J. Biol. Chem. 263, 343-346). This thermostable, acidic protein has a molecular weight of 17,000 ...
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We measured pharmacologically isolated GABAergic currents from layer II/III neurons of the rat auditory cortex using patch-clamp recording. Activation of muscarinic receptors by muscarine (1 μM) or oxotremorine (10 μM) decreased the amplitude of electrically evoked inhibitory postsynaptic currents to about one third of their control value. Neither miniature nor exogenously-evoked GABAergic curr...
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Recent evidence suggests the expression of a Na(+)/Ca(2+) exchanger (NCX) in vascular endothelial cells. To elucidate the functional role of endothelial NCX, we studied Ca(2+) signaling and Ca(2+)-dependent activation of endothelial nitric-oxide synthase (eNOS) at normal, physiological Na(+) gradients and after loading of endothelial cells with Na(+) ions using the ionophore monensin. Monensin-...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 2001
ISSN: 0022-3751,1469-7793
DOI: 10.1111/j.1469-7793.2001.0583h.x